Alumna follows unexpected path to meaningful career

Alumna takes on new role at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

By Nicole La Hoz
Caroline Cox-Signore, MD ‘92, is surrounded by her classmates during their 10-year reunion in Gainesville with the late Dr. Hugh “Smiley” Hill in 2002.

Caroline Cox-Signore, MD ‘92, is surrounded by her classmates during their 10-year reunion in Gainesville with the late Dr. Hugh “Smiley” Hill in 2002.

It was a new beginning for Caroline Cox-Signore, MD ’92, MPH.

While the Eunice Kennedy Shriver National Institute of Child Health and Human Development, where she had worked since 2003, was undergoing a major reorganization, a division of extramural research was created, and Signore was tapped to be its deputy director.

Signore, who completed her OB-GYN residency at UF, has served in that role since January, assisting the division’s director in overseeing the institute’s extramural research program.

“Everything I learned from UF prepared me for that day I took the plunge,” Signore said. “It prepared me for the day I said, ‘I’m back in the game. Here’s what I can do.’”

Soon after completing her OB-GYN residency in 1996, Signore moved to Denver with her husband and joined a private practice in general obstetrics and gynecology.

But four months into her new life, plans stopped.

Signore was in a car accident that severed her C-6 vertebrae, leaving her paralyzed with limited upper body movement.

It took four months to complete inpatient rehabilitation and “wrap (my) head around what happened,” Signore said.

When her husband received a job offer in Washington, D.C., they relocated. Again, Signore struggled to find a career path.

That’s when she began to take interest in government, public service and policy. Although she couldn’t practice, Signore became a board-certified obstetrician-gynecologist and applied for an American Congress of Obstetricians and Gynecologists-sponsored fellowship that allowed her to enroll in the master’s of public health program at George Washington University in 2002.

With a specialization in maternal and child health and health policy, Signore became a summer intern at the NICHD and continued as a postdoctoral fellow in the division of epidemiology, statistics and prevention research, studying the identification of genetic, nutritional and biochemical risk factors for birth defects.

When a full-time medical officer position opened in the pregnancy and perinatology branch in 2006, she was selected. It’s what led Signore to her current position today.

“Even though I wasn’t physically capable of being the doctor I imagined I’d be, I discovered that there’s more than one way to be a doctor,” she said.

“From an upside-down, total car wreck in ‘96, I now have a title for the first time in my life.”